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學歷
美國伊利諾州立大學生物工程系博士
國立清華大學化學工程系學士
現職及與專長相關之經歷
現職：國立清華大學生命科學系助理教授
經歷：美國史丹佛大學醫學系血液科博士後研究員
莊永仁實驗室研究領域
1.
心血管內皮層細胞功能障礙和相關疾病之研究
2.
癌細胞藉由血管侵襲和轉移之機制
3.
病原與宿主系統之交互作用
近五年內發表之學術性著作
1.Chen ML, Adak AK, Yeh NC, Yang WB, Chuang YJ, Wong CH, Hwang KC, Hwu JR, Hsieh, SL, Lin CC. Fabrication of an Oriented Fc-Fused Lectin Microarray through Boronate Formation. Angew Chem Int Ed Engl. 2008 Oct 10; 47(45):8627-8630. [Epub ahead of print] No abstract available. PMID:18850623
2.Chen BS, Yang SK, Lan CY, Chuang YJ. A systems biology approach to construct the gene regulatory network of systemic inflammation via microarray and databases mining. BMC Med Genomics. 2008 Sep 30;1:46. PMID:18823570
3.Chen BS, Chang CH, Chuang YJ. Robust model matching control of immune systems under environmental disturbances:dynamic game approach. J Theor Biol. 2008 Aug 21;253(4):824-37. Epub 2008 Apr 29. PMID: 18534627
4.Zhang W, Chuang YJ, Jin T, Swanson R, Xiong Y, Leung L, Olson ST.(2006) Antiangiogenic antithrombin induces global changes in the gene expression profile of endothelial cells. Cancer Research, 66(10):5047-55.
5.Zhang W, Chuang YJ, Swanson R, Li J, Seo K, Leung L, Lau LF, Olson ST. (2004) Antiangiogenic antithrombin down-regulates the expression of the proangiogenic heparan sulfate proteoglycan, perlecan, in endothelial cells.Blood. 103(4):1185-91.
6.Bedsted T, Swanson R, Chuang YJ, Bock PE, Bjork I, Olson ST. (2003) Heparin and calcium ions dramatically enhance antithrombin reactivity with factor IXa by generating new interaction exosites. Biochemistry.42(27):8143-52.
7.Olson ST, Chuang YJ. (2002) Heparin activates antithrombin anticoagulant function by generating new interaction sites (exosites) for blood clotting proteinases. Trends in Cardiovascular Medicine. 12(8):331-8.Review.
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